General Wellness

CONVALESCENT PLASMA – LIES, DAMN LIES AND STATISTICS.

Andrew Chuma No Comments

CONVALESCENT PLASMA – LIES, DAMN LIES AND STATISTICS.
 
Early in the pandemic, one of the treatments for infected and hospitalized Covid patients was convalescent plasma. Plasma, also known as serum, is the fluid portion of blood (most cells removed) which contains all kinds of other stuff, including clotting proteins, nutrients, enzymes and antibodies. In the case of recovered Covid patients, it contains antibodies to the SARS Cov-2 virus. The rationale for it helping other patients is that the antibodies in the plasma would inactivate viruses in the recipient’s body. These are called “neutralizing” antibodies. Although there seemed to be some benefit to giving them plasma, none of these patients ONLY received convalescent plasma. They received many treatments so it’s impossible to know how much it helped by itself. It makes sense that it would help.
 
The FDAs knee-jerk reaction in approving its Emergency Use Authorization is another example of the administration not understanding the science and shooting before assessing fully. The statistics were manipulated and expressed in a way that made plasma look much more effective than it really is.
 
In addition, the way data is expressed can be deceptive and misleading. That is what the CDC did when they made the announcement about how beneficial convalescent plasma really was. The NIH, National Institutes of Health, pointed out the inaccuracies but the damage is done. Those who want to believe in a magic cure are there already.
 
If it helps, it is limited to recently infected/affected patients. Late administration is probably useless since there is too much viral load to manage. This is another reason to support testing. If we identify patients early, and it turns out that convalescent plasma is significantly effective, it can be administered at an adequate stage of infection rather than missing the chance.
 
In addition to not having statistically significant benefits, there are risks like allergic reactions or contracting another infection like HIV or Hepatitis C, both of which are transmitted in plasma if not screened properly.
 
Just to be clear, I’m not saying that convalescent plasma is bad or ineffective. And I would probably take it if I was that sick and it was offered. However, it’s no miracle cure.
 
There is NO miracle cure. Not Zithromax, Hydroxychloroquin, plasma, zinc, not even Kale, although a healthy, plant-based diet definitely has many advantages with NO side effects.
 
In the meantime, do what we KNOW is helpful:
 
WEAR A MASK. Wear it properly covering your nose. As an aside, the shields some people wear are not that effective. It’s OK to wear, just wear a mask underneath.
DISTANCE APPROPRIATELY
WASH OUR HANDS
GET HEALTHY
VENTILATE
 
And one more important one to add to this list:
 
GET YOUR FLU SHOT. EVERYONE, not just older and sicker people or people at risk because of work. You don’t want a double whammy.
 
Stay safe and be well.
AC 😎✌️🌱❤🐖🏃🏻🧘🏻‍♂️🌎😷
 

Inspired and disappointed

Andrew Chuma 2 comments

Inspired and disappointed.

After a week off, it’s back to the grind and the insanity!

After dropping off our youngest at college in Ann Arbor, we spent the rest of the week at the beach, spending some great distanced beach-time with friends and family. I was inspired by friends who had contracted Covid, had gotten through and were still willing to interact with appropriate precautions (masks and distancing). Unfortunately, our approach to Covid early on in the pandemic has resulted in some excessive paranoia in some people. We need to socialize, just do it safely. I was also quite touched and inspired by friends who were volunteering for vaccine trials. I also have a number of friends in the medical, dental and education worlds who continue to see patients and teach our kids, albeit with major changes in their routines. All brave and selfless. There are many essential workers who continue to do their jobs, making our lives easier.

Unfortunately, within only a few hours of seeing patients Monday morning after the week off, my jaw tightness returned. I was hoping for more of a reprieve. 

The anxiety experienced by patients is also in full swing. Most problems I see are magnified one way or another by either needing to wear a mask, which impacts on communications, or the stress of life during a pandemic, complicated by social unrest, political craziness in addition to the stresses of regular life, creeping into their daily routines.

Everyone is experiencing significant stress at some level. We just need to get through it. Together.

After limiting my news/media consumption, I was surprised by the absence of anything really new on the covid front. More of the same. 

Poor governmental leadership. Rather than pointing fingers at the scientists and distorting the science, our leaders need to promote the basics like social responsibility by mask wearing and distancing appropriately. They should also be promoting healthful lifestyle changes. Instead we are pummeled by ads like Kraft who think that Mac N’ Cheese for breakfast is a good thing!

There are also confusing CDC guidelines, who now recommend NOT testing as much, especially if you are not symptomatic? I disagree.

Conspiracy-theorist flamed lies about “overexaggerated” Covid-19 deaths! Completely ridiculous. If someone dies of a heart attack because of the stress Covid-19 caused, it’s STILL a Covid-19 related death. If you just compare deaths overall in the US since Covid-19 started and ignore coronavirus-associated deaths, we still have more than 200,000 deaths than the same timeframe last year. To think that this is just “chronic disease” is either ridiculously sad and Americans are sicker than they think or something else is causing these deaths, like…. maybe….. Covid-19?. 

I did read about some interesting new symptoms associated with Covid, both acutely and long term.

  • More rapidly growing finger and toe nails while losing more hair (the hair one has been known).
  • Worsening headaches, probably due to a combination of infections and stress.
  • Sun sensitivity like rashes and easy burning. By the way, Zithromax, the antibiotic (it is NOT an antiviral) promoted by our administration, is well known to cause sun sensitivity also.
  • Tinnitus. Sounds in the head or the ears is most commonly a result of hearing loss or damage to the very complex sound analysis mechanisms in the brain, It is often worsened by stress so how Covid-19 increases tinnitus is not clear since overt hearing loss has not been seen yet as a specific complication.

There is continued interest in vaccine trials, more of which are entering phase 3. But unfortunately, surveys still indicate that up to 40% of people would not take a vaccine if it became available. This is sad since, if we want to achieve herd immunity, the estimates are that 80-90% need to be vaccinated. Otherwise, it will continue to circulate continuously, just like the flu. Unlike the flu however, SARS-Cov-2 seems to do just as well in the warmer months as the colder ones so it will be around ALL year rather than just in the winter!

Many confusing issues but I need to start by reinforcing the well-established basics:

WEAR A MASK. It protects you and it protects everyone else.

DISTANCE appropriately and avoid crowded areas.

WASH YOUR HANDS and use sanitizer appropriately.

GET HEALTHY. This remains the least promoted aspect of all this. The sicker you are, the greater the risks.

VENTILATION. This will become more and more important as the weather cools and we start spending more time indoors. Contracting is dependent on exposure.

Stay safe and be well. 

AC 😎✌️🌱❤🐖🏃🏻🧘🏻‍♂️🌎😷

⇑ Back to Top ⇑